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Article

Localization of complement 1 inhibitor (C1INH/SERPING1) in human eyes with age-related macular degeneration.

Experimental eye research - 1 Nov 2009

Mullins Robert F, Faidley Elizabeth A, Daggett Heather T, Jomary Catherine, Lotery Andrew J, Stone Edwin M

Abstract excerpt

Age-related macular degeneration (AMD) is a common degenerative disease resulting in injury to the retina, retinal pigment epithelium and choriocapillaris. Recent data from histopathology, animal models and genetic studies have implicated altered regulation of the complement system as a major factor in the incidence and progression of this disease. A variant in the gene SERPING1, which encodes C1INH, an inhibitor...

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Source

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Identifiers

PMID: 19607829
DOI: 10.1016/j.exer.2009.07.001
PMCID: PMC2757497

Genes

SERPING1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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