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Article

Common variation in the SERPING1 gene is not associated with age-related macular degeneration in two independent groups of subjects.

Molecular vision - 1 Jan 2009

Park Kyu Hyung, Ryu Euijung, Tosakulwong Nirubol, Wu Yanhong, Edwards Albert O

Abstract excerpt

PURPOSE: Common genetic variation in the complement component 1 inhibitor gene (SERPING1) was recently reported to increase the risk of developing age-related macular degeneration (AMD). This study was performed to replicate the association between SERPING1 and AMD. METHODS: Seven single nucleotide polymorphisms (SNPs) tagging common haplotypes across SERPING1 were genotyped on 786 (The Mayo Clinic) subjects and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19169411
PMCID: PMC2629736

Genes

SERPING1
ARMS2
CFB
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variation in the SERPING1 gene is not associated with age-related macular degeneration in two independent groups of subjects.PMID 19169411Read ↗

An association study of SERPING1 gene and age-related macular degeneration in a Han Chinese population.Semantic proximity Read ↗

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.Semantic proximity Read ↗

The effect of genetic variants in SERPING1 on the risk of neovascular age-related macular degeneration.Semantic proximity Read ↗

Association between the SERPING1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese.Semantic proximity Read ↗

Distribution of risk alleles in patients with age-related macular degeneration.Semantic proximity Read ↗

Ethnic differences in the association of SERPING1 with age-related macular degeneration and polypoidal choroidal vasculopathy.Semantic proximity Read ↗

Determination of a gene and environment risk model for age-related macular degeneration.Semantic proximity Read ↗

Relationship between SERPING1 rs2511989 polymorphism and age-related macular degeneration risk: a meta-analysis.Semantic proximity Read ↗

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No Sex Differences in the Frequencies of Common Single Nucleotide Polymorphisms Associated with Age-Related Macular Degeneration.Semantic proximity Read ↗

Variation in complement component C1 inhibitor in age-related macular degeneration.Semantic proximity Read ↗

Genetic variation in complement regulators and susceptibility to age-related macular degeneration.Semantic proximity Read ↗

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