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Article

Genetic variation in complement regulators and susceptibility to age-related macular degeneration.

Immunobiology - 1 Feb 2012

Cipriani Valentina, Matharu Baljinder K, Khan Jane C, Shahid Humma, Stanton Chloe M, Hayward Caroline, Wright Alan F, Bunce Catey, Clayton David G, Moore Anthony T, Yates John R W

Abstract excerpt

OBJECTIVES: Age-related macular degeneration (AMD) is the commonest cause of blindness in Western populations. Risk is influenced by age, genetic and environmental factors. Complement activation appears to be important in the pathogenesis and associations have been found between AMD and genetic variations in complement regulators such as complement factor H. We therefore investigated other complement regulators...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22024702
DOI: 10.1016/j.imbio.2011.09.002
PMCID: PMC3657157

Genes

CFP
CFB
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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