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Article

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.

Lancet (London, England) - 22 Nov 2008

Ennis Sarah, Jomary Catherine, Mullins Robert, Cree Angela, Chen Xiaoli, Macleod Alex, Jones Stephen, Collins Andrew, Stone Edwin, Lotery Andrew

Abstract excerpt

BACKGROUND: Age-related macular degeneration is the most prevalent form of visual impairment and blindness in developed countries. Genetic studies have made advancements in establishing the molecular cause of this disease, identifying mutations in the complement factor H (CFH) gene and a locus on chromosome 10 encompassing the HTRA1/LOC387715/ARMS2 genes. Variants in complement 3 (C3) and an HLA locus containing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18842294
DOI: 10.1016/S0140-6736(08)61348-3
PMCID: PMC5983350

Genes

SERPING1
ARMS2
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.PMID 18842294Read ↗

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