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Complement-Mediated Events in Alzheimer’s Disease: Mechanisms and Potential Therapeutic Targets

1 Jan 2020

Abstract excerpt

An estimated 5.7 million Americans suffer from Alzheimer's disease in the United States, with no disease-modifying treatments to prevent or treat cognitive deficits associated with the disease. Genome-wide association studies suggest that an enhancement of clearance mechanisms and/or promotion of an anti-inflammatory response may slow or prevent disease progression. Increasing awareness of distinct roles of...

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PMID: 31907273
DOI: 10.4049/jimmunol.1901068

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