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Article

Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation.

Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2011

Neacsu Cristian Dan, Grosch Melanie, Tejada Mercedes, Winterpacht Andreas, Paulsson Mats, Wagener Raimund, Tagariello Andreas

Abstract excerpt

UCMA (alternatively named GRP) is a novel member of the family of γ-carboxyglutamate (Gla) containing proteins that is mainly expressed in cartilage. We have used the zebrafish as a model organism to study UCMA function. Due to the whole genome duplication two Ucma genes are present in zebrafish, ucmaa and ucmab, located on chromosomes 25 and 4, respectively. UCMA gene structure, alternative splicing and protein...

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Source

Identifiers

PMID: 21839171
DOI: 10.1016/j.matbio.2011.07.002

Genes

UCMA
GRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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