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Article

Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene.

1 Sept 1990

Abstract excerpt

Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. MGP is also expressed at high levels in heart, kidney, and lung and is up-regulated by vitamin D in bone cells. To characterize the genomic sequences responsible for the regulated expression of this gene, we screened a human genomic library using a MGP cDNA probe and obtained two clones containing the MGP...

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PMID: 2394711
DOI: 10.1016/s0021-9258(18)77221-9

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Source receipt: pubmed, retrieved 7 Sept 2026.

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