Article
Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes).
Journal of molecular evolution - 1 Aug 2004
Imanishi Yoshikazu, Yang Lili, Sokal Izabela, Filipek Slawomir, Palczewski Krzysztof, Baehr Wolfgang
Abstract excerpt
The guanylate cyclase-activating proteins (GCAPs) are Ca(2+)-binding proteins of the calmodulin (CaM) gene superfamily that function in the regulation of photoreceptor guanylate cyclases (GCs). In the mammalian retina, two GCAPs (GCAP 1-2) and two transmembrane GCs have been identified as part of a complex regulatory system responsive to fluctuating levels of free Ca(2+). A third GCAP, GCAP3, is expressed in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.