Article
Human metastable epiallele candidates link to common disorders.
Epigenetics - 1 Feb 2013
Harris R Alan, Nagy-Szakal Dorottya, Kellermayer Richard
Abstract excerpt
Metastable epialleles (MEs) are mammalian genomic loci where epigenetic patterning occurs before gastrulation in a stochastic fashion leading to systematic interindividual variation within one species. Importantly, periconceptual nutritional influences may modulate the establishment of epigenetic changes, such as DNA methylation at MEs. Based on these characteristics, we exploited Infinium HumanMethylation450...
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