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Article

Environmental epigenomics in human health and disease.

Environmental and molecular mutagenesis - 1 Jan 2008

Dolinoy Dana C, Jirtle Randy L

Abstract excerpt

The epigenome consists of the DNA methylation marks and histone modifications involved in controlling gene expression. It is accurately reproduced during mitosis and can be inherited transgenerationally. The innate plasticity of the epigenome also enables it to be reprogrammed by nutritional, chemical, and physical factors. Imprinted genes and metastable epialleles represent two classes of genes that are...

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PMID: 18172876
DOI: 10.1002/em.20366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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