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Article

Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease.

Archives of neurology - 1 Aug 2011

Cruchaga Carlos, Nowotny Petra, Kauwe John S K, Ridge Perry G, Mayo Kevin, Bertelsen Sarah, Hinrichs Anthony, Fagan Anne M, Holtzman David M, Morris John C, Goate Alison M

Abstract excerpt

BACKGROUND: Apolipoprotein E (APOE) is the most statistically significant genetic risk factor for late-onset Alzheimer disease (LOAD). The linkage disequilibrium pattern around the APOE gene has made it difficult to determine whether all the association signal is derived from APOE or whether there is an independent signal from a nearby gene. OBJECTIVE: To attempt to replicate a recently reported association of...

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Source

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Identifiers

PMID: 21825236
DOI: 10.1001/archneurol.2011.155
PMCID: PMC3204798

Genes

APOE
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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