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Article

An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease.

Archives of neurology - 1 May 2010

Roses Allen D

Abstract excerpt

I coauthored a recently published research article describing a variable length, poly-T polymorphism in the TOMM40 gene, adjacent to apolipoprotein E (APOE) on chromosome 19, that accounts for the age at onset distribution for a complex disease, late-onset Alzheimer disease. These new data explain the mean age at disease onset for patients with the APOE4/4 genotype and differentiate 2 forms of TOMM40 poly-T...

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Share to Age of Onset
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Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 19

Share to DNA Repeat Expansion

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Share to Membrane Transport Proteins

Share to Mitochondrial Precursor Protein Import Complex Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20457951
DOI: 10.1001/archneurol.2010.88
PMCID: PMC3140162

Genes

TOMM40
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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