Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.

doi:10.1001/archneurol.2012.2052

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Article

Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.

Archives of neurology - 1 Oct 2012

Jun Gyungah, Vardarajan Badri N, Buros Jacqueline, Yu Chang-En, Hawk Michele V, Dombroski Beth A, Crane Paul K, Larson Eric B, Mayeux Richard, Haines Jonathan L, Lunetta Kathryn L, Pericak-Vance Margaret A, Schellenberg Gerard D, Farrer Lindsay A

Abstract excerpt

OBJECTIVE: To evaluate the association of risk and age at onset (AAO) of Alzheimer disease (AD) with single-nucleotide polymorphisms (SNPs) in the chromosome 19 region including apolipoprotein E (APOE) and a repeat-length polymorphism in TOMM40 (poly-T, rs10524523). DESIGN: Conditional logistic r...

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Identifiers

PMID: 22869155
DOI: 10.1001/archneurol.2012.2052
PMCID: PMC3579659

Genes

APOE
TOMM40

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22869155-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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