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Article

The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 May 2018

Chiba-Falek Ornit, Gottschalk William K, Lutz Michael W

Abstract excerpt

The TOMM40 poly-T is a polymorphism in intron 6 of the TOMM40 gene, which is adjacent to and in linkage disequilibrium with APOE. Roses et al. identified the association between the length of TOMM40 poly-T with the risk and age of onset of late-onset Alzheimer's disease (LOAD). Following the original discovery, additional studies found associations between the TOMM40 poly-T and LOAD-related phenotypes independent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29524426
DOI: 10.1016/j.jalz.2018.01.015
PMCID: PMC5938113

Genes

TOMM40
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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