Article
High dosage of the small nucleolar RNA snR10 specifically suppresses defects of a yeast rrp5 mutant.
Molecular genetics and genomics : MGG - 1 Sept 2002
Torchet C, Hermann-Le Denmat S
Abstract excerpt
We have previously described a yeast strain in which cleavage at site A2 during processing of rRNA is absent and is functionally replaced by cleavage at site A3. This strain expresses a variant of the essential RRP5 gene that results in the synthesis of two noncontiguous segments of the protein. We have used the slow-growth phenotype of this strain to screen for revertants. The gene for the small nucleolar RNA...
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