Article
Genome screen for bone mineral density phenotypes in Fisher 344 and Lewis rat strains.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2005
Koller Daniel L, Alam Imranul, Sun Qiwei, Liu Lixiang, Fishburn Tonya, Carr Lucinda G, Econs Michael J, Foroud Tatiana, Turner Charles H
Abstract excerpt
In humans, peak bone mineral density (BMD) is the primary determinant of osteoporotic fracture risk among older individuals, with high peak BMD levels providing protection against osteoporosis in the almost certain event of bone loss later in life. A genome screen to identify quantitative trait loci (QTLs) contributing to areal BMD (aBMD) and volumetric BMD (vBMD) measurements at the lumbar spine and femoral neck...
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