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Article

Genetic regulation of bone traits is influenced by sex and reciprocal cross in F(2) progeny from GK and F344 rats.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2009

Lagerholm Sofia, Li Luo-Sheng, Jiao Hong, Park Hee-Bok, Ohlsson Claes, Akesson Kristina, Luthman Holger

Abstract excerpt

A genome-wide linkage analysis to identify quantitative trait loci (QTLs) for bone phenotypes was performed in an F(2) intercross of inbred spontaneously type 2 diabetic GK and normoglycemic F344 rats (108 males and 98 females). The aim of the study was to locate genome regions with candidate genes affecting trabecular and cortical bone and to investigate the effects of sex and reciprocal cross. pQCT was used to...

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Identifiers

PMID: 19113924
DOI: 10.1359/jbmr.081252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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