Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy.

Circulation research - 16 Sept 2011

Wang Sheng-Bing, Foster D Brian, Rucker Jasma, O'Rourke Brian, Kass David A, Van Eyk Jennifer E

Abstract excerpt

RATIONALE: Cardiac resynchronization therapy (CRT) is an effective clinical treatment for heart failure patients with conduction delay, impaired contraction, and energetics. Our recent studies have revealed that mitochondrial posttranslational modifications (PTM) may contribute to its benefits, motivating the present study of the oxidative regulation of mitochondrial ATP synthase. OBJECTIVES: We tested whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cysteine
Share to Disulfides
Share to Glutathione

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heart Failure

Share to Mitochondria, Heart

Share to Mitochondrial Proton-Translocating ATPases

Share to Myocardium

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 21817160
DOI: 10.1161/CIRCRESAHA.111.246124
PMCID: PMC3500591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy.PMID 21817160Read ↗

Post‐translational modifications of the cardiac proteome in diabetes and heart failureSemantic proximity Read ↗

Functional decorations: post-translational modifications and heart disease delineated by targeted proteomicsSemantic proximity Read ↗

Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathySemantic proximity Read ↗

Reductive Stress Linked to Small HSPs, G6PD, and Nrf2 Pathways in Heart DiseaseSemantic proximity Read ↗

Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic HeartSemantic proximity Read ↗

PITX2C Deficiency Promotes Arrhythmogenic Remodeling via Oxidative Stress in Atrial MyocytesSemantic proximity Read ↗

Nitrosative stress leads to protein glutathiolation, increased s-nitrosation, and up-regulation of peroxiredoxins in the heart.Semantic proximity Read ↗

Does reversible cysteine oxidation link the Western diet to cardiac dysfunction?Semantic proximity Read ↗

Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria.Semantic proximity Read ↗

Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice.Semantic proximity Read ↗

Reversible oxidative modification: a key mechanism of Na+-K+ pump regulation.Semantic proximity Read ↗

Identification of Protein Disulfide Isomerase as a Cardiomyocyte Survival Factor in Ischemic CardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.