Article
Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria.
Molecular & cellular proteomics : MCP - 1 Feb 2011
Deng Ning, Zhang Jun, Zong Chenggong, Wang Yueju, Lu Haojie, Yang Pengyuan, Wang Wenhai, Young Glen W, Wang Yibin, Korge Paavo, Lotz Christopher, Doran Philip, Liem David A, Apweiler Rolf, Weiss James N, Duan Huilong, Ping Peipei
Abstract excerpt
Mitochondrial functions are dynamically regulated in the heart. In particular, protein phosphorylation has been shown to be a key mechanism modulating mitochondrial function in diverse cardiovascular phenotypes. However, site-specific phosphorylation information remains scarce for this organ. Accordingly, we performed a comprehensive characterization of murine cardiac mitochondrial phosphoproteome in the context...
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