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Article

Reductive Stress Linked to Small HSPs, G6PD, and Nrf2 Pathways in Heart Disease

3 Sept 2012

Abstract excerpt

SIGNIFICANCE: Aerobic organisms must exist between the dueling biological metabolic processes for energy and respiration and the obligatory generation of reactive oxygen species (ROS) whose deleterious consequences can reduce survival. Wide fluctuations in harmful ROS generation are circumvented by endogenous countermeasures (i.e., enzymatic and nonenzymatic antioxidants systems) whose capacity decline with aging...

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PMID: 22938199
DOI: 10.1089/ars.2012.4914

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