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Article

Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?

Parkinsonism & related disorders - 1 Dec 2011

Biernacka Joanna M, Armasu Sebastian M, Cunningham Julie M, Ahlskog J Eric, Chung Sun Ju, Maraganore Demetrius M

Abstract excerpt

BACKGROUND: Polymorphisms in SNCA, MAPT and LRRK2 genes have recently been confirmed as risk factors for Parkinson's disease (PD), although with small individual attributable risk. Here we investigated the association of PD with interactions between variants of these genes. METHODS: As part of a previous study of PD susceptibility genes 119 SNCA, MAPT, and LRRK2 haplotype tagging single nucleotide polymorphisms...

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Source

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Identifiers

PMID: 21816655
DOI: 10.1016/j.parkreldis.2011.07.001
PMCID: PMC4723425

Genes

MAPT
SNCA

Provenance

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