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Article

An exploratory analysis on gene-environment interactions for Parkinson disease.

Neurobiology of aging - 1 Oct 2012

Gao Jianjun, Nalls Michael A, Shi Min, Joubert Bonnie R, Hernandez Dena G, Huang Xuemei, Hollenbeck Albert, Singleton Andrew B, Chen Honglei

Abstract excerpt

Little is known about gene-environment interactions in Parkinson disease (PD). We examined potential interactions of smoking and caffeine intake with 10 genome-wide association studies single nucleotide polymorphisms (SNPs) at or near the SNCA, MAPT, LRRK2, and HLA loci among 584 PD patients and 1571 controls. The main effects of these SNPs and environmental exposures were consistent with previous reports. Family...

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Source

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Identifiers

PMID: 22763023
DOI: 10.1016/j.neurobiolaging.2012.06.007
PMCID: PMC3419385

Genes

MAPT
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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