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Article

A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.

PLoS biology - 1 Jul 2011

Seidel Hannah S, Ailion Michael, Li Jialing, van Oudenaarden Alexander, Rockman Matthew V, Kruglyak Leonid

Abstract excerpt

The evolutionary fate of an allele ordinarily depends on its contribution to host fitness. Occasionally, however, genetic elements arise that are able to gain a transmission advantage while simultaneously imposing a fitness cost on their hosts. We previously discovered one such element in C. elegans that gains a transmission advantage through a combination of paternal-effect killing and zygotic self-rescue. Here...

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Identifiers

PMID: 21814493
DOI: 10.1371/journal.pbio.1001115
PMCID: PMC3144186

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