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Article

Divergent C. elegans toxin alleles are suppressed by distinct mechanisms.

eLife - 11 Aug 2026

Zdraljevic Stefan, Walter-McNeill Laura, Bruni Giancarlo N, Bloom Joshua S, Collins J B, Leighton Daniel H W, Marquez Heriberto, Alexander Noah, Kruglyak Leonid

Abstract excerpt

Toxin-antidote elements (TAs) are selfish DNA sequences that bias their transmission to the next generation. TAs typically consist of two linked genes: a toxin and an antidote. The toxin kills progeny that do not inherit the TA, while the antidote counteracts the toxin in progeny that inherit the TA. We previously discovered two TAs in Caenorhabditis elegans that follow the canonical TA model of two linked genes:...

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Identifiers

PMID: 42578454
DOI: 10.7554/eLife.106269
PMCID: PMC13461147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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