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Article

The type I membrane protein EFF-1 is essential for developmental cell fusion.

Developmental cell - 1 Mar 2002

Mohler William A, Shemer Gidi, del Campo Jacob J, Valansi Clari, Opoku-Serebuoh Eugene, Scranton Victoria, Assaf Nirit, White John G, Podbilewicz Benjamin

Abstract excerpt

Multinucleate cells are widespread in nature, yet the mechanism by which cells fuse their plasma membranes is poorly understood. To identify animal fusogens, we performed new screens for mutations that abolish cell fusion within tissues of C. elegans throughout development. We identified the gene...

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PMID: 11879640
DOI: 10.1016/s1534-5807(02)00129-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11879640-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The type I membrane protein EFF-1 is essential for developmental cell fusion.PMID 11879640Read ↗

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EFF-1 promotes muscle fusion, paralysis and retargets infection by AFF-1-coated viruses in <i>C. elegans</i>Semantic proximity Read ↗

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