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Article

Mutations affecting the meiotic and mitotic divisions of the early Caenorhabditis elegans embryo.

Genetics - 1 Nov 1990

Mains P E, Kemphues K J, Sprunger S A, Sulston I A, Wood W B

Abstract excerpt

We describe interactions between maternal-effect lethal mutations in four genes of Caenorhabditis elegans whose products appear to be involved in the meiotic and mitotic divisions of the one-cell embryo. Mitosis is disrupted by two dominant temperature-sensitive gain-of-function maternal-effect lethal mutations, mei-1(ct46) and mel-26(ct61), and by recessive loss-of-function maternal-effect lethal mutations of...

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Identifiers

PMID: 2249759
DOI: 10.1093/genetics/126.3.593
PMCID: PMC1204215

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