Article
KIRigami: the case for studying NK cell receptors in SIV+ macaques.
Immunologic research - 1 Jan 2008
Bimber Benjamin, O'Connor David H
Abstract excerpt
Genes of the major histocompatibility complex (MHC) are one of the most significant genetic predictors of HIV and SIV disease outcome; however, in no case is MHC genotype alone sufficient to account for this durable HIV/SIV control. Killer immunoglobulin-like receptors (KIRs) interact with MHC molecules and have been implicated in control of HIV replication. They provide an attractive candidate to act in concert...
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