Article
In vivo effects of cytokines on development of natural killer cells and antitumor activity in lethally irradiated bone marrow transplanted recipients.
Journal of biological response modifiers - 1 Feb 1990
Riccardi C, Migliorati G, Cannarile L, D'Adamio F, Frati L, Herberman R B
Abstract excerpt
We have evaluated the effects of combinations of various cytokines on the reconstitution of natural killer (NK) cell activity and resistance to metastases from B16 melanoma, in lethally irradiated mice transplanted with syngeneic bone marrow. Treatment with some combinations of interleukin-2 (IL-...
Topics
- Animals
- Antineoplastic Agents
- Biological Factors
- Bone Marrow Transplantation
- Cell Division
- Combined Modality Therapy
- Complement System Proteins
- Cytokines
- Cytotoxicity Tests, Immunologic
- Female
- Growth Substances
- Killer Cells, Natural
- Male
- Melanoma, Experimental