Article
Effect of various cytokine combinations on induction of non-MHC-restricted cytotoxicity.
Lymphokine and cytokine research - 1 Jun 1993
Morecki S, Nagler A, Puyesky Y, Nabet C, Condiotti R, Pick M, Gan S, Slavin S
Abstract excerpt
Efforts were directed to achieve an increased lymphokine-activated non-MHC-restricted killing (LAK) activity greater than that induced by rIL-2 alone. Human peripheral blood (PB) and bone marrow (BM)-derived mononuclear cells (MC) were exposed in vitro to multiple cytokine combinations, including rIL-6, rIL-7, rIFN-alpha and rIFN-gamma in the presence of either suboptimal or optimal doses of rIL-2. Our results...
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