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Article

Combination treatment using thymosin alpha 1 and interferon after cyclophosphamide is able to cure Lewis lung carcinoma in mice.

Cancer immunology, immunotherapy : CII - 1 Jan 1990

Garaci E, Mastino A, Pica F, Favalli C

Abstract excerpt

A combination treatment with thymosin alpha 1 (200 micrograms/kg) for 4 days, followed by a single injection of murine interferon alpha/beta (3 x 10(4) international units/mouse). starting 2 days after cyclophosphamide treatment (200 mg/kg, single injection) demonstrated a dramatic and rapid disa...

Topics

Animals
Antineoplastic Combined Chemotherapy Protocols
Cell Survival
Cyclophosphamide
Cytotoxicity, Immunologic
Immunotherapy
Interferon Type I
Interferon-gamma
Killer Cells, Natural
Lung Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred Strains

Phenotype

Thymalfasin

Thymosin

Source

Open in PubMed Open full text

Identifiers

PMID: 2126987
DOI: 10.1007/BF01771450
PMCID: PMC11038037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2126987-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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