Article
Immunogenetics of mycobacterial infections: mouse-human homologies.
The Journal of infectious diseases - 1 Apr 1990
Schurr E, Buschman E, Malo D, Gros P, Skamene E
Abstract excerpt
In the mouse, innate resistance or susceptibility to infection with numerous mycobacteria is controlled by the Bcg host resistance locus located on the centromeric region of chromosome 1. The resistance/susceptibility phenotype is expressed by the mature tissue macrophage and Bcg has been identified as a locus that is involved in the regulation of macrophage activation and in the modulation of acquired immune...
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