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Article

Genetic control of susceptibility to mycobacterial infections.

Reviews of infectious diseases - 1 Jan 2000

Skamene E

Abstract excerpt

Susceptibility of mice to the establishment of infection after exposure to mycobacteria is controlled by a single, dominant, autosomal gene: the Bcg gene. It is located on the centromeric portion of chromosome 1 within a linkage group that shows structural homology with a conserved region of human chromosome 2. The Bcg gene regulates directly the process of T cell-independent macrophage activation for...

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PMID: 2496454
DOI: 10.1093/clinids/11.supplement_2.s394

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Source receipt: pubmed, retrieved 7 Sept 2026.

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