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Article

Genetic control of innate resistance to mycobacterial infections.

Immunology today - 1 Mar 1991

Schurr E, Malo D, Radzioch D, Buschman E, Morgan K, Gros P, Skamene E

Abstract excerpt

The Mendelian segregation of resistance to infection in different strains of mice infected with mycobacteria, Salmonella and Leishmania spp, all of which live in macrophages, is currently under close scrutiny. Here, Erwin Schurr and colleagues review the nature and function of the Bcg gene in controlling innate resistance to mycobacterial infection in mice and speculate on the occurrence of a possible human...

Topics

Animals
Chromosome Mapping
Gene Expression Regulation
Genes, Dominant
Genetic Markers
Humans
Immunity, Innate
Leprosy
Macrophage Activation
Macrophages
Mice
Mycobacterium Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Tuberculosis

Source

Identifiers

PMID: 2069678
DOI: 10.1016/S0167-5699(05)80012-X

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2069678-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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