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Article

Wild type N-ras displays anti-malignant properties, in part by downregulating decorin.

Journal of cellular physiology - 1 Jun 2012

Benet Marta, Dulman Robin Yates, Suzme Raffi, de Miera Eleazar Vega-Saenz, Vega Martha E, Nguyen Thuy, Zavadil Jiri, Pellicer Angel

Abstract excerpt

Previously, we have shown that wild type N-ras (wt N-ras) harbors an anti-malignant effect against mutated Ras and in tumors without Ras mutations. To investigate the molecular bases of this anti-malignant activity, we have studied the potency of this anti-malignant effect in a model system against SV40 large T antigen (SV40T). We show that wild-type N-ras (wt N-ras) counteracts the effects of SV40T in NIH3T3...

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Identifiers

PMID: 21809347
DOI: 10.1002/jcp.22969
PMCID: PMC3212639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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