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Article

Suppression of the malignant phenotype of melanoma cells by anti-oncogene ribozymes.

The Journal of investigative dermatology - 1 Feb 1996

Ohta Y, Kijima H, Kashani-Sabet M, Scanlon K J

Abstract excerpt

The activation of signal transduction pathways by mutation or overexpression of cellular oncogenes has been associated with neoplastic transformation. In this study, we addressed the therapeutic potential of ribozymes targeted against the activated H-ras oncogene as well as against the nuclear proto-oncogenes c-fos and c-myc in the FEM human melanoma cell line containing a H-ras mutation. FEM cells transfected...

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Identifiers

PMID: 8601728
DOI: 10.1111/1523-1747.ep12340688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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