Article
Altered glycosylation in Madin-Darby canine kidney (MDCK) cells after transformation by murine sarcoma virus.
Clinical & experimental metastasis - 1 Jan 2000
Bruyneel E A, Debray H, De Mets M, Mareel M M, Montreuil J
Abstract excerpt
The changes in glycosylation of an immortalized epithelial cell line (MDCK) before and after progression towards a more malignant phenotype have been studied. The parental MDCK-3 cells were immortalized after long-term passage in vitro and have shown no tendency for spontaneous acquisition of malignancy-related phenotypes such as tumorigenicity, invasion and metastasis. They conserved morphological and functional...
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