Article
Suppression of the neoplastic phenotype in vivo by an anti-ras ribozyme.
Cancer research - 15 Feb 1994
Kashani-Sabet M, Funato T, Florenes V A, Fodstad O, Scanlon K J
Abstract excerpt
In this study, the efficacy of an anti-ras ribozyme in reversing the neoplastic phenotype was investigated. Murine NIH3T3 cells were transfected with cellular DNA from the FEMX-I human melanoma cell line expressing the activated H-ras gene. The transformed cells displayed the neoplastic phenotype...
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