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Article

Frequency of genetic polymorphisms of PXR gene in the Brazilian population.

Clinics (Sao Paulo, Brazil) - 1 Jan 2011

Moreira Ricardo P P, Jorge Alexander A L, Mendonca Berenice B, Bachega Tânia A S S

Abstract excerpt

INTRODUCTION: PXR polymorphisms have been implicated in modulating CYP3A4 and PXR expression, potentially accounting for interindividual differences in drug metabolism. The prevalence of PXR polymorphisms varies among ethnic groups and data on the allelic distribution in the highly mixed Brazilian population is lacking. The aim of this study was to analyze genetic variations in the PXR gene in Brazilians and to...

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Identifiers

PMID: 21808872
DOI: 10.1590/s1807-59322011000600020
PMCID: PMC3129971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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