Article
Genetic variability of PXR in Saudi Arabians.
Biochemical genetics - 1 Aug 2013
Al-Dosari Mohammed S, Alkharfy Khalid M, Alghamdi Amal M, Al-Mohizea Abdullah M, Al-Jenoobi Fahad I, Al-Muhsen Saleh, Halwani Rabih, Parvez M Khalid, Khalid Parvez M
Abstract excerpt
Polymorphisms in the PXR gene play important roles in influencing the efficacy and toxicity of a large number of endogenous and exogenous substrates. Because of ethnic specificity, several studies have been directed toward the determination of PXR polymorphisms in various populations. In the current study, we determined the genotype and allele frequencies of 19 coding and regulatory polymorphisms in the PXR gene...
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