Article
Lack of mutations in K-ras codons 12 and 13 in human atherosclerotic lesions.
Chemico-biological interactions - 27 Sept 1996
Bogliolo M, Fronza G, Campomenosi P, Assereto P, Izzotti A, Petrilli G L, Abbondandolo A, De Flora S
Abstract excerpt
In the framework of a project investigating the possible involvement of cancer biomarkers in human atherogenesis, we evaluated the occurrence of K-ras mutations in the DNA extracted from smooth muscle cells of abdominal aorta atherosclerotic lesions. The molecular analysis of the DNA from 32 surg...
Topics
- Aged
- Aged, 80 and over
- Animals
- Aorta, Abdominal
- Arteriosclerosis
- Base Sequence
- Cell Line
- Codon
- DNA
- Female
- Genes, ras
- Humans
- Male
- Mice
- Middle Aged
- Molecular Sequence Data
- Mutation
- Nucleic Acid Heteroduplexes