Article
[Somatic mutations of the P53 gene in stomach cancer].
Voprosy onkologii - 1 Jan 2010
Beliavskaia V A, Vardosanidze K V, Oreshkova S F, Blinov A G, Ternovoĭ V A, Blinov V M, Cherdyntseva N V, Voevoda M I
Abstract excerpt
The paper deals with a study of p53 gene somatic mutations in tumor cell genomes from patients with stomach cancers of different histological patterns. It used sequential and molecular cloning methods. The former involved amplicones characterized by abnormal volatility following SSCP analysis of plasmids from 9 tumors. Replacement nucleotides were identified in 4 tumors (intestinal--2, diffuse--2). Among 8...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
