Article
A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma.
PloS one - 1 Jan 2011
Campayo Marc, Navarro Alfons, Viñolas Nuria, Tejero Rut, Muñoz Carmen, Diaz Tania, Marrades Ramon, Cabanas Maria L, Gimferrer Josep M, Gascon Pere, Ramirez Jose, Monzo Mariano
Abstract excerpt
MicroRNAs (miRNAs) play an important role in carcinogenesis through the regulation of their target genes. miRNA-related single nucleotide polymorphisms (miR-SNPs) can affect miRNA biogenesis and target sites and can alter microRNA expression and functions. We examined 11 miR-SNPs, including 5 in microRNA genes, 3 in microRNA binding sites and 3 in microRNA-processing machinery components, and evaluated time to...
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