Article
A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma.
Gene - 15 Apr 2014
Xie Ying, Diao Lanping, Zhang Li, Liu Chao, Xu Zengnian, Liu Shufeng
Abstract excerpt
MicroRNA (miRNA), which plays an important role in tumorigenesis, can regulate post-transcriptional gene expression by binding to the 3' untranslated regions (3'-UTRs) of messenger RNAs and repressing its translation. Several single nucleotide polymorphisms (SNPs) are considered to have significant impacts on susceptibility of the role these genetic polymorphisms in development of carcinogenesis through that...
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