Article
Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy.
Oncotarget - 7 Jun 2016
Chen Xingming, Sturgis Erich M, Wang Chengyuan, Cao Xiaoli, Li Yuncheng, Wei Qingyi, Li Guojun
Abstract excerpt
Common single nucleotide polymorphisms (SNPs) in miRNAs may affect miRNA functions and their target expression and thus may affect biological activities and cancer etiology as well as prognosis. Thus, we determined whether the 9 SNPs in microRNAs modify the risk of recurrence of squamous cell carcinoma of the oropharynx (SCCOP) in a cohort of 1008 patients. The log-rank test and multivariate Cox models were used...
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