Article
A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma.
Cancer research - 15 Aug 2013
Zheng Jian, Deng Jieqiong, Xiao Mang, Yang Lei, Zhang Liyuan, You Yonghe, Hu Min, Li Na, Wu Hongchun, Li Wei, Lu Jiachun, Zhou Yifeng
Abstract excerpt
Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is little information on individual genetic factors to help predict and improve patient outcomes. Single-nucleotide polymorphisms (SNP) in mature microRNA (miRNA) sequences have the potential to exert broad impact as miRNAs target many mRNAs. The aim of this study was to evaluate the effects of SNPs in mature miRNA sequences on...
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