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Article

Genetic variations in epigenetic genes are predictors of recurrence in stage I or II non-small cell lung cancer patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2012

Wagner Klaus W, Ye Yuanqing, Lin Jie, Vaporciyan Ara A, Roth Jack A, Wu Xifeng

Abstract excerpt

PURPOSE: Early-stage non-small cell lung cancer (NSCLC) is potentially curable, however, many patients develop recurrent disease. Therefore, identification of biomarkers that can be used to predict patient's risk of recurrence and survival is critical. Genetic polymorphisms or single-nucleotide polymorphisms (SNP) of DNA- and histone-modifying genes, particularly those of O(6)-methylguanine DNA-methyltransferase...

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Share to Carcinoma, Non-Small-Cell Lung
Share to Chemotherapy, Adjuvant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to DNA-Cytosine Methylases

Share to Epigenesis, Genetic

Share to Kaplan-Meier Estimate

Share to Neoplasm Recurrence, Local

Share to Neoplasm Staging

Source

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Identifiers

PMID: 22252258
DOI: 10.1158/1078-0432.CCR-11-2087
PMCID: PMC3373176

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MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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