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Article

CTLA-4 gene polymorphism of exon 1(+49 A/G) in Turkish systemic lupus erythematosus patients.

International journal of immunogenetics - 1 Aug 2009

Ulker M, Yazisiz V, Sallakci N, Avci A B, Sanlioglu S, Yegin O, Terzioglu E

Abstract excerpt

Cytotoxic T lymphocyte-associated antigen-4 is a cell-surface molecule providing a negative signal for T cell activation. CTLA-4 gene polymorphisms are known to be related with genetic susceptibility to various autoimmune diseases, including systemic lupus erythematosus (SLE). However, the effects of this polymorphism on clinical features of SLE have not been defined. We analysed the CTLA-4 gene +49 A/G...

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Identifiers

PMID: 19602000
DOI: 10.1111/j.1744-313X.2009.00856.x

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