Article
c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.
Nucleic acids research - 1 Nov 2011
Mathad Raveendra I, Hatzakis Emmanuel, Dai Jixun, Yang Danzhou
Abstract excerpt
We studied the structures and stabilities of G-quadruplexes formed in Myc1234, the region containing the four consecutive 5' runs of guanines of c-MYC promoter NHE III(1,) which have recently been shown to form in a supercoiled plasmid system in aqueous solution. We determined the NMR solution structure of the 1:2:1 parallel-stranded loop isomer, one of the two major loop isomers formed in Myc1234 in K(+)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.