Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes.

Biophysical journal - 16 Mar 2011

Dettler Jamie M, Buscaglia Robert, Le Vu H, Lewis Edwin A

Abstract excerpt

We completed a biophysical characterization of the c-MYC proto-oncogene P1 promoter quadruplex and its interaction with a cationic porphyrin, 5,10,15,20-tetra(N-methyl-4-pyridyl)porphyrin (TMPyP4), using differential scanning calorimetry, isothermal titration calorimetry, and circular dichroism s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calorimetry, Differential Scanning
Share to G-Quadruplexes
Share to Nucleic Acid Denaturation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Porphyrins

Share to Proto-Oncogene Proteins c-myc

Share to Purines

Share to Thermodynamics

Share to Transition Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 21402034
DOI: 10.1016/j.bpj.2011.01.068
PMCID: PMC3059730

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21402034-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes.PMID 21402034Read ↗

Stability and kinetics of c-MYC promoter G-quadruplexes studied by single-molecule manipulation.Semantic proximity Read ↗

Biophysical characterization of an ensemble of intramolecular i-motifs formed by the human c-MYC NHE III1 P1 promoter mutant sequence.Semantic proximity Read ↗

Identification of a G-quadruplex forming sequence in the promoter of UCP1.Semantic proximity Read ↗

Epigenetic mutations: Effects on the stability of G-quadruplex structures in the c-KIT promoter.Semantic proximity Read ↗

An improved model for the hTERT promoter quadruplex.Semantic proximity Read ↗

c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.Semantic proximity Read ↗

The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern.Semantic proximity Read ↗

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics.Semantic proximity Read ↗

Electrocatalytic monitoring of metal binding and mutation-induced conformational changes in p53 at picomole level.Semantic proximity Read ↗

Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1.Semantic proximity Read ↗

G-quadruplex formation in the Oct4 promoter positively regulates Oct4 expression.Semantic proximity Read ↗

p53 binds human telomeric G-quadruplex in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.