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Article

Functional and phenotypic characteristics of alternative activation induced in human monocytes by interleukin-4 or the parasitic nematode Brugia malayi.

Infection and immunity - 1 Oct 2011

Semnani Roshanak Tolouei, Mahapatra Lily, Moore Vanessa, Sanprasert Vivornpun, Nutman Thomas B

Abstract excerpt

Human monocytes from patients with patent filarial infections are studded with filarial antigen and express markers associated with alternative activation of macrophages (MΦ). To explore the role of filaria-derived parasite antigen in differentiation of human monocytes, cells were exposed to microfilariae (mf) of Brugia malayi, and their phenotypic and functional characteristics were compared with those of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21788379
DOI: 10.1128/IAI.05191-11
PMCID: PMC3187236

Genes

CCL15
CCL17
CCL18
CCL22
CCL13
MRC1
TLR3
TLR5
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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